The domain within your query sequence starts at position 1270 and ends at position 1386; the E-value for the 2vxg domain shown below is 3e-18.
FQQALTAADLNLVLYVCETVDPAQVFGQPPCPLSQPVLLSLIQQLASDLGTRSDLKLSYL EEAVMHLDHSDPITRDHMGSVMAQVRQKLFQFLQADPHNSLSKAARRLSLMLHGLVT